Pick a boss and difficulty — get the verified loadout that this site recommends, with primary weapon, backup, consumables, and tactical notes. Cross-references every boss-specific guide on this site.
Loadout recommendations cross-reference every boss-specific strategy guide on this site, plus the All Bosses Ranked tier list. Each weapon-to-boss recommendation has been verified through actual playthroughs on PS5 and Steam, with Insanity loadouts re-tested after the v1.02 patch verification pass (see v1.02 Patch Diary).
The Insanity loadouts assume you have access to Infinite Ammo from the Special Content Store (post-clear unlock). If you're attempting Insanity without Infinite Ammo as a personal challenge, expect each boss to take 2-3x longer and require 50% more consumables.
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