What is the Best Boss Strategy in RE9?

Author note: Written by Jachin, a 23-year Resident Evil series fan based in Seoul, South Korea. This guide is based on 6 full RE9 playthroughs on PS5 and Steam (Casual β†’ Insanity β†’ NG+ Insanity completions). All strategies, timings, and locations have been personally tested across the v1.02 patch. AI tools were used only for grammar review and note organization; no AI-generated content appears in strategy analysis.

Verified on: v1.02 + DLC patch Β· Last reviewed: May 30, 2026 Β· About the author Β· Editorial policies

PUBLISHED JUNE 2026 Β· QUICK ANSWER Β· v1.02 VERIFIED
βœ“ SPOILER LEVEL: LOW

Short answer: Universal strategy: Magnum headshots + Shotgun close-range + Knife parries. Equip Crafter's Touch + Iron Skin + Phoenix Down charms. Specific boss strategies below. All 10 bosses have detailed guides linked.

The universal boss strategy

  1. Pre-fight prep: Stock 8-12 Magnum rounds, 4-6 Shotgun shells, 3 First Aids minimum
  2. Charm loadout: Crafter's Touch + Iron Skin + Phoenix Down
  3. Opening: Magnum to head until first phase transition
  4. Mid-fight: Shotgun close-range during low-mobility phases
  5. Closing: Knife parry for execution / cutscene triggers

Boss-specific best strategies

Victor Gideon (Final Boss)

Best strategy: Magnum headshots Phase 1-2 (4 headshots), Shotgun close-range Phase 3, knife parry for QTE finale (0.4-second window).

Full Victor Gideon guide β†’

Mr. X / Super Tyrant

Best strategy: Circle-strafe, never back-pedal. Use RPD pillars for 90Β° cover. Shotgun close-range during stagger. 6 Magnum rounds total.

Full Mr. X guide β†’

Chunk (Final Encounter)

Best strategy: AR full-auto on arms (break both for execution opening). Shotgun for Phase 2 mutation. Magnum to head for Phase 3 truth reveal.

Full Chunk guide β†’

Plant 43

Best strategy: AR full-auto on 3 root clusters (15 rounds each). Avoid spore cloud β€” run to room edge. Flame rounds skip Phase 2.

Full Plant 43 guide β†’

Titan Spinner

Best strategy: Sidestep last-second (0.3s before charge). Climb east fire escape Phase 2. Grenades knock down (15% HP each). Free-fall finisher.

Full Titan Spinner guide β†’

The Girl

Best strategy: Bloodhound charm to track. Stealth approach (must be unalerted). Back-blast Shotgun for first hit. Drowning execution = True Ending.

Full The Girl guide β†’

The Commander

Best strategy: Wait for shield drop (every 4s) β†’ Magnum headshot. Shotgun for twin ad spawns. Phoenix Down activates if you die.

Full Commander guide β†’

Blister Borne

Best strategy: 5m distance maintain. Handgun whittle. Sprint behind cover during pop (360Β° AOE). Knife-only kill = Predator charm.

Full Blister Borne guide β†’

The Chef (Optional)

Best strategy: Don't pick up meat lures. Predictable knife arcs β€” sidestep + reply fire. Knife counter-stab does double damage.

Full The Chef guide β†’

Insanity-specific boss tactics

See our bosses tier list for difficulty rankings and detailed boss analyses.

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